Between Our Genes and Our Dendrites: The Making or Breaking of Humans

 Nadene Goldfoot                                           

  Today's DNA scientists, perhaps at Family Tree DNA in Houston, Texas.  They show me that my ancient origins show the autosomal DNA I carry from ancient European groups are:  28% hunter-gatherers;  50% farmers;  22% metal-age invaders.  

Scientists can examine our genes by putting our spit under something like a microscope.  Our genes are in all our cells of our body.  To be exact, DNA, or deoxyribonucleic acid, is the blueprint of life, the sequence of chemicals that defines each human being as unique.

 Twins, but not identical twins: Esau, born 1st with ruddy complexion,  and then Jacob who was to become the father of 12 sons:  the 12 tribes of Israel, for Jacob's name changed to Israel when he struggled or wrestled with a heavenly emissary and overcame him, being then given the name, Israel.  Each twin is so unique.  

Think of Isaac and Rebekah who had their twin sons, Esau and Jacob, 20 years after they were married. The Bible says he was 100 years old and when "his eyes were too dim to see", when he called his eldest son, Esau, to give him his last blessing recognizing his birthright.  Their DNA were obviously closer than any other brothers or sisters would be, but still carried some different genes as well. Isaac was the son of Abraham who was born in about 1948 BCE, about 4,000 years ago. They had accumulated far less genes than we carry today.  I suppose they were in the hunting-gathering stage. 

In this example, Isaac and Rebekah were 1st cousins, so their DNA overlapped. Terah was the father of Abraham and Rebekah's father was Bethel  who was also a son of Terah.  Rebekah's brother was Laban, the man that her son, Jacob, worked for in order to marry Rachel.  He had been working for his uncle.    

Twin brothers married twin sisters and they bore sons who look alike.  Amazing!   

Actually, "Identical twins form from the same egg and get the same genetic material from their parents — but that doesn't mean they're genetically identical by the time they're born.

That's because so-called identical twins pick up genetic mutations in the womb, as their cells weave new strands of DNA and then split into more and more cells. 

On average, pairs of twins have genomes that differ by an average of 5.2 mutations that occur early in development, according to a new study." 

Human DNA contains 3,147 million chemical nucleotide bases (A,G, C,T).  The total length of DNA present in one adult human is about 2x10"13  meters, the distance from the earth to the sun and back.  The DNA in an average chromosome-we have 23 of those, is about 5cm long.  Almost all (99.9%) nucleotide bases are exactly the same in all people;  and 97% are the same as the chimpanzee's.

Dendrites are part of our brain.   Hopefully, we have grown a lot of them.   Dendrites are appendages that are designed to receive communications from other cells. They resemble a tree-like structure, forming projections that become stimulated by other neurons and conduct the electrochemical charge to the cell body (or, more rarely, directly to the axons).  The more we use our brain to solve problems, the more dendrites we grow.  They're like the star we earn for every puzzle we solve.  Einstein must have had a lot of them as his IQ was 180, with 100 being average.  

Willis suggests that the most pleasant and rewarding way to increase your dendrites is to “meet and interact with intelligent, interesting people.” Try tournament bridge, chess, even sailboat racing. And remember, researchers agree that it's never to late."                        

Science has shown that mankind went into hunting when first becoming humans.  After he wised up, he became farmers.  But did you ever wonder why our Native Americans were still at the  hunters' stage  when the Mayflower landed in 1620?  They hadn't gone through the farming stage that Europeans had.

             Grinding corn they grew, made own pottery, too

The exceptions were  a few more isolated tribes such as the Pueblo who lived in higher housing and couldn't get out to hunt as well.  They resorted to growing corn and that saved them.  Traditionally, Pueblo peoples were farmers, with the types of farming and associated traditions of property ownership varying among the groups. Along the Rio Grande and its tributaries, corn (maize) and cotton were cultivated in irrigated fields in river bottoms. Among the western Puebloans, especially the Hopi, farming was less reliable because there were few permanent water sources. Traditionally, women did most of the farming, but as hunting diminished in importance, men also became responsible for agricultural work.

It has long been thought that prior to white settlement, Indigenous Australians lived a nomadic, hunter-gatherer lifestyle. Now some scholars argue that the first Australians practised forms of agriculture and aquaculture, writes Cathy Pryor.  Some evidence is that they grew bananas, states another reference.

When Great Britain sent their criminals into exile in Australia, they also found a people different from themselves.  They were the "Aboriginal Australians who are the various Indigenous peoples of the Australian mainland and many of its islands, such as Tasmania, Fraser Island, Hinchinbrook Island, the Tiwi Islands, and Groote Eylandt, but excluding the Torres Strait Islands." As they tell us,  "Aboriginal and Torres Strait Islander peoples are the proud keepers of arguably the oldest continuous culture on the planet. Our heritage spans many different communities, each with its own unique mixture of cultures, customs and languages. Before the European invasion in 1788 there were more than 250 Indigenous nations, each with several clans.  Were they hunters or gatherers or farmers?  "Our people were great storytellers, passing on their cultures through songlines – an animist belief system expressed through songs, stories, paintings and dance. We were also expert hunters and gatherers and had sophisticated ways of taking care of the land.  The prevailing theory was that they had not yet gone through the farming stage.  

It seems that different people progressed according to how fast their particular DNA warranted the speed which was controlled by the dendrites, or vice-versa.  Necessity is said to be the mother of all invention, so it may be that necessity causes how fast our bodies react; as threat-free environment allows us to just live and enjoy.  

Our holy writings and legends all tell us that we came from Adam and Eve, one man and one woman, and this particular woman also came from Adam;  his rib, as a matter of fact, so she shared his DNA.  Yet, the sons of Adam haven't all developed at the same time nor at the same places other than knowing human life started in Africa. 

In fact, science is now thinking that before our stone age period, our paternal ancestor was something more like an Orangutan (tree man)  who was able to walk on two feet.  He lived in trees and finally came down, and he's the father of all of us;  going back extremely far, of course, and this came about after studying the remains of bones of the leg.  Orangutans are great apes native to the rainforests of Indonesia and Malaysia. They are now found only in parts of Borneo and Sumatra, but during the Pleistocene they ranged throughout Southeast Asia and South China. Classified in the genus Pongo, orangutans were originally considered to be one species.                                 

Intelligence comes from having the right genes and the use of our brains.  Having the right genes but being lazy about using your mind will get you nowhere.  A person who is constantly using his mind and learning, even as he or she ages, are using what they have, and need not worry about what genes they have inherited, except if their ancestors suffered from dementia a lot.  

Intelligence isn't everything, either.  One has had to have ambition and guts to get things accomplished, or the right friends in the right places and a lot of money for pay-offs.  

All this has to be dependent on our ecosystem; the water and nutrients in the soil that we eventually ingest.  This should have something to do with what kind of people we turn out to be. 

Animals are either getting smarter or always have been smart.

Wolfgang Kohler, the psychologist in 1920, observed that chimpanzees not only used tools to reach food, but that they could also make tools to reach food. 

Jane Goodall observed chimps in the 1960s doing so in the wild.  Until then, it was thought that only humans were able to make tools.  

We now know that Dolphins have a language, elephants mourn their dead, and even cats and dogs reason in their own cat and dog ways.  Dogs have been known to save their masters' lives in one way or another.  Bees communicate the way to the nearest flower through a kid of bee-dance.   

This all means that the modern day expectant mothers should be taking all the nutrients that modern medicine has to offer  in order to produce the best and healthiest child possible, and stay away from all the bad things like drugs, smoking, and alcohol. We don't want to be surpassed by the animals.  We are to stay on top.  

In the end, it's those genes and our environment that have made us who we are, and that environment helped to create all the dendrites that we had collected.  One seemed to affect the other.  We couldn't do much about the genes we inherited, but all through our lives, we are either prisoners or partners of our environment. Go and enjoy life.   

  

Resource:

DNA & Genealogy by Colleen Fitzpatrick & Andrew Yeiser

The New Standard Jewish Encyclopedia

https://www.intoxicatedonlife.com/all-the-twins-in-the-bible/

https://www.amnesty.org.au/eight-facts-about-indigenous-people-in-australia/?cn=trd&mc=click&pli=23501504&PluID=0&ord={timestamp}&gclid=CjwKCAjwv4SaBhBPEiwA9YzZvJ2lSoFf5ltre5GWcrxftKwacr4xDo5d1F0CNP9xlzgKC2V1mJbt_xoCJ0IQAvD_BwE

youtube on orangutan father of us all

https://www.britannica.com/topic/Pueblo-Indians

https://www.abc.net.au/radionational/programs/archived/bushtelegraph/rethinking-indigenous-australias-agricultural-past/5452454

https://www.sdbif.org/articles/dendrites_grow.pdf

https://en.wikipedia.org/wiki/Orangutan

Our Jewish Genes As the Geneticists See them

 Nadene Goldfoot                                               

Recent studies have been conducted on a large number of genes, homologous chromosomes or autosomes (all chromosomes except chromosomes X and Y). We have 23 chromosomes and the X and Y, the 23rd, are the sex genes with X being female and Y being the male line.   Actually, we have 46; 23 from each parent.  

These 46 chromosomes carry the genetic information that’s passed from parent to child through heredity. It is the very detail of this genetic material – in the DNA – that makes most people (other than identical siblings) totally unique.

The total number of chromosomes in an organism, such as an animal or plant, is important and differs for different species. Some insects, for instance, only have one or two chromosomes. Meanwhile, giraffes have 62, chickens have 78, mice have 40, cabbages 18, and strawberries only 14. Humans, like many other species, are called ‘diploid’. This is because our chromosomes exist in matching pairs – with one chromosome of each pair being inherited from each biological parent.

Every cell in the human body contains 23 pairs of such chromosomes; our diploid number is therefore 46, our ‘haploid’ number 23. Of the 23 pairs, 22 are known as autosomes. The 23rd pair is made up of the sex chromosomes, called the ‘X’ and ‘Y’ chromosome. This is the pair of chromosomes that is responsible for ‘sex-linked’ medical conditions that pass through some families, such as the blood disorder haemophilia, which affects mainly males. Females have a pair of X chromosomes, males have an X and Y chromosome. 

A 2009 study was able to genetically identify individuals with full or partial Ashkenazi Jewish ancestry.  

Harry Ostrer is a medical geneticist who investigates the genetic basis of common and rare disorders. In the diagnostic laboratory, he translates the findings of genetic discoveries into tests that can be used to identify people's risks for disease prior to occurrence, or for predicting its outcome once it has occurred. He is also known for his study, writing and lectures on the origins of the Jewish people.

He is a Professor of Pathology and Genetics at Albert Einstein College of Medicine of Yeshiva University and Director of Genetic and Genomic Testing at Montefiore Medical Center.

For the prior 21 years he was Professor of Pediatrics, Pathology and Medicine and Director of the Human Genetics Program at New York University School of Medicine.

 In August 2012, Dr. Harry Ostrer in his book Legacy: A Genetic History of the Jewish People, summarized his and other work in genetics of the last 20 years, and concluded that all major Jewish groups share a common Middle Eastern origin. Ostrer also refuted the Khazar hypothesis of Ashkenazi ancestry. 

Citing autosomal DNA studies, Nicholas Wade estimates that "Ashkenazic and Sephardic Jews have roughly 30 percent European ancestry, with most of the rest from the Middle East." He further noticed that "The two communities seem very similar to each other genetically, which is unexpected because they have been separated for so long." Concerning this relationship he points to Atzmon's conclusions that "the shared genetic elements suggest that members of any Jewish community are related to one another as closely as are fourth or fifth cousins in a large population, which is about 10 times higher than the relationship between two people chosen at random off the streets of New York City".

 Concerning North African Jews, autosomal genetic analysis in 2012 revealed that North African Jews are genetically close to European Jews. This finding "shows that North African Jews date to biblical-era Israel, and are not largely the descendants of natives who converted to Judaism,

" Y DNA studies examine various paternal lineages of modern Jewish populations. Such studies tend to imply a small number of founders in an old population whose members parted and followed different migration paths.

 In most Jewish populations, these male line ancestors appear to have been mainly Middle Eastern. For example, Ashkenazi Jews share more common paternal lineages with other Jewish and Middle Eastern groups than with non-Jewish populations in areas where Jews lived in Eastern Europe, Germany and the Rhine Valley. This is consistent with Jewish traditions in placing most Jewish paternal origins in the region of the Middle East.                  

Doron M. Behar, Founder and CEO of Igentify | Genetics and genomics enthusiast | Committed to advancing the digital genomic revolution, Haifa, Israel, said, "I am a population geneticist and physician dedicated to changing the way that genetic information is uncovered and used. I’m working to bring digital health, genomics, and technology together, alongside my colleagues at Igentify. We help clinicians, laboratories, and patients access, interpret, and use genetic information and education more effectively. I’m proud to lead Igentify in its work generating optimism for change and synergizing the genomic and digital revolutions. I enjoy collaborating with others who share our vision for actionable and accessible genomic data for all.

A study conducted in 2013 by Doron  M. Behar, 

MD, PhD et al. found no evidence of a Khazar origin for Ashkenazi Jews and suggested that "Ashkenazi Jews share the greatest genetic ancestry with other Jewish populations, and among non-Jewish populations, with groups from Europe and the Middle East. No particular similarity of Ashkenazi Jews with populations from the Caucasus is evident, particularly with the populations that most closely represent the Khazar region. In this view, analysis of Ashkenazi Jews, together with a large sample from the region of the Khazar Khaganate, corroborates earlier results that Ashkenazi Jews derive their ancestry primarily from populations of the Middle East and Europe, that they possess considerable shared ancestry with other Jewish populations, and that there is no indication of a significant genetic contribution either from within or from north of the Caucasus region."

 THE CANAANITES

A 2020 study on remains from Bronze Age southern Levantine (Canaanite) populations found evidence of large scale migration from the Zagros or Caucasus into the southern Levant by the Bronze Age and increasing over time (resulting in a Canaanite population descended from both those migrants and earlier Neolithic Levantine peoples). 

The results were found to be consistent with several Jewish groups (including Mizrahi, Ashkenazi, and Sephardic Moroccan Jews) and non-Jewish Arabic-speaking Levantine populations (such as Lebanese, Druze, Palestinians, and Syrians) deriving about half or more of their ancestry from populations related to those from the Bronze Age Levant and Chalcolithic Zagros. The study modeled the aforementioned groups as having ancestry from both ancient populations. (So it's the non-Jewish genes they share.)

Approximately 35% to 43% of Jewish men are in the paternal line known as haplogroup J and its sub-haplogroups. This haplogroup is particularly present in the Middle East and Southern Europe. 15% to 30% are in haplogroup E1b1b, (or E-M35) and its sub-haplogroups which is common in the Middle East, North Africa, and Southern Europe.                                   

                                        Israeli Jews

Israeli Jews belong by and large to the Ashkenazi (German, Central and Eastern European) division of world Jews, although there are minority representations from the Sephardic (Spanish) and Mizrahi (Middle Eastern) divisions. They number over 6 million inhabitants and comprise 75% of the population of the Middle Eastern state of Israel, founded in 1949. The overwhelming majority are non-Haredi or not strictly Orthodox by religion. Ethnically and genetically, they derive from European populations that were largely eliminated during the Holocaust and are thus no longer present in significant numbers in present-day European nations. European Jewry after World War II was transplanted and has been divided almost equally between Israel and the United States. See Demographics of Israel.

The Israeli Jews population data represent DNA samples from 163 unrelated mixed Jewish Caucasians of both sexes obtained by the Department of Human Genetics, Tel-Aviv University, Israel in 2004. A European Standard Set (ESS) of DNA loci was used, compiling allele distributions for 10 short tandem repeat (STR) polymorphic markers as used in forensic and paternity testing with the commercial AmpFISTR SGM Plus kit developed by Applied Biosystems.

Treasures of Jewish Art: From the Jacobo and Asea Furman Collection of Judaica, possibly Sepharic 

In 1992 G. Lucotte and F. David were the first genetic researchers to have documented a common paternal genetic heritage between Sephardi and Ashkenazi Jews. Another study published just a year later suggested the Middle Eastern origin of Jewish paternal lineages.

Michael Hammer, PhD, is a professor and research scientist.  Dr. Hammer is a Research Scientist in the ARL Division of Biotechnology at the University of Arizona with joint appointments in Neurology and Ecology and Evolutionary Biology, and is a member of the Steele Children’s Research Center, Bio5, and the Arizona Cancer Center. Dr. Hammer’s research spans the fields of medical genetics and human population genetics. For the past 20 years, Dr. Hammer’s group has published over 100 articles documenting the African origin of human diversity, interbreeding between modern humans and archaic forms of the genus Homo, and genome diversity in the great apes. In the last 3 years, his research team has successfully employed next generation sequencing technologies to identify genetic variants causing neurodevelopmental disorders in undiagnosed children. This has led to the publication of articles identifying pathogenic variants associated with early onset epileptic encephalopathies. His lab is also pursuing studies to identify modifier genes that alter the expression of major genes and how they contribute to the molecular basis of clinical variability in Mendelian disorders.

In 2000, Michael Hammer, PhD,, et al. conducted a study on 1,371 men and definitively established that part of the paternal gene pool of Jewish communities in Europe, North Africa and Middle East came from a common Middle East ancestral population. They suggested that most Jewish communities in the Diaspora remained relatively isolated and endogamous compared to non-Jewish neighbor populations.

Investigations made by Nebel et al. on the genetic relationships among Ashkenazi Jews, Kurdish and Sephardi (North Africa, Turkey, Iberian Peninsula, Iraq and Syria) indicate that Jews are more genetically similar to groups in the northern Fertile Crescent (Kurds, Turks and Armenians) than their Arab neighbors, and suggest that some of this difference might be due to migration and admixture from the Arabian peninsula during the last two millennia (into certain current Arabic-speaking populations). Considering the timing of this origin, the study found that "the common genetic Middle Eastern background (of Jewish populations) predates the ethnogenesis in the region and concludes that the Y chromosome pool of Jews is an integral part of the genetic landscape of Middle East.

                       Priestly families:Cohanim

                                                             

Born in Canada, Prof. Karl Skorecki’s current major research interests are in human population and molecular genetics, having started with research studies tracing founding patrilineal and matrilineal lineages in Near East and Jewish populations which has now extended to genome-wide studies including many global populations, with an emphasis on kidney disease population disparities. His research has been reported in leading scientific and medical journals and books with more than 250 publications and close to 8000 citations. Prof. Skorecki has delivered multiple endowed lectures at leading universities throughout the world and at premiere scientific conferences. He has served and continues to serve on numerous institutional, national, and international advisory boards and committees, and most recently was elected as a member of the council of the Israel Science Foundation. Prof. Karl Skorecki is the Dean of Bar-Ilan University’s Azrieli Faculty of Medicine in Safed, Israel. 

Nephrologist Dr. Karl Skorecki decided to analyze the Cohanim to see if they were the descendants of one man, in which case they should have a set of common genetic markers.

To test this hypothesis, he contacted Dr. Michael Hammer of the University of Arizona, a researcher in molecular genetics and a pioneer in research on chromosomes. Their article, published in Nature in 1997, has had some impact. A set of special markers (called Cohen Modal Haplotype or CMH) was defined as one which is more likely to be present in the Cohanim, defined as contemporary Jews named Cohen or a derivative, and it was proposed that this results from a common descent from the ancient priestly lineage than from the Jewish population in general.

But, subsequent studies showed that the number of genetic markers used and the number of samples (of people saying Cohen) were not big enough. The last study, conducted in 2009 by Hammer and Behar et al., says 20 of the 21 Cohen haplogroups have no single common young haplogroup; five haplogroups comprise 79.5% of all haplogroups of Cohen. Among these first 5 haplogroups, J-P58 (or J1E) accounts for 46.1% of Cohen and the second major haplogroup, J-M410 or J2a accounts for 14.4%.

 Hammer and Behar have redefined an extended CMH haplotype as determined by a set of 12 markers and having as "background" haplogroup determining the most important lines J1E (46.1%). This haplotype is absent among non-Jews in 2009 analyzed in the study. This divergence would appear to be from 3000 ± 1000 years ago. This study nevertheless confirms that the current Cohen lineage descended from a small number of paternal ancestors.

In the summary of their findings the authors concluded that " Our estimates of the coalescence time also lend support to the hypothesis that the extended CMH represents a unique founding lineage of the ancient Hebrews that has been paternally inherited along with the Jewish priesthood."

Molecular phylogenetics research published in 2013 and 2016 for Levant haplogroup J1 (J-M267) places the Y-chromosomal Aaron within subhaplogroup Z18271, age estimate 2638–3280 years Before Present (yBP). Moses was born in 1391 BCE, so Aaron, his brother, was born in 1395 BCE, which was 3,417 years ago., fitting in with 3,280 time frame of the scientists.

A leader of the Lemba people, wearing a prayer shawl, gathers with his fellow Jews. DNA tests have confirmed the Semitic heritage of these sub-Saharan Africans.

Jekesai Njikizana /AFP/Getty Images

The Lemba of South Africa, a Bantu speaking people whose culture forbids pork and requires male circumcision, have high frequencies of the Middle Eastern Y-chromosome HgJ-12f2a (25%), a potentially SEA Y, Hg-K(xPQR) (32%) and a Bantu Y, E-PN1 (30%) (similar to E-M2). The Lemba tribe of Venda in South Africa claims to be Jewish and to have originated in Sena – possibly Yemenite Sena in Wadi Masila of the Hadramaut. There are indications of genetic connections with the Hadramaut, i.e., the Lemba Y-chromosomes and Hadramaut Y-chromosomes showed overlap. In addition, there was also present a Cohen Modal Haplotype (CMH) within their subclan, the Buba – higher than the general Jewish population. It has been suggested by Tudor Parfitt and Yulia Egorova that their Jewish ancestors probably came along with general Semitic incursions into East Africa from South Arabia, and then moved slowly south through the area of Great Zimbabwe.

Resource:

https://en.wikipedia.org/wiki/Genetic_studies_on_Jews#:~:text=in%20one%20sample.-,Y%2DDNA%20of%20Ethiopian%20Jews,Ethiopia%2C%20not%20the%20Middle%20East.

https://dnaconsultants.com/israeli-jews/

https://neurology.arizona.edu/michael-hammer-phd

https://il.linkedin.com/in/doron-m-behar-md-phd-b8b0ba137

https://www.jewishvirtuallibrary.org/zimbabwe-s-quot-black-jews-quot-the-lemba-people

More On Origins Of Q's Y Haplogroup's Origins of Anatolia (Turkey)-Part II On Hittites

 More on Origins of Q's Y haplogroup's origins of Turkey-Part II on Hittite Possibile Origins

 Nadene Goldfoot                                           

  Q-  YHaplogroup Area:  Notice a narrow band along Israel on the Mediterranean Sea

Our Jewish line, determined by my brother,  of Q happens to be Q-BZ67 with origins originally from Siberia, Mongolia and parts of Turkey. It was first labeled as Q-M242, and Q -Y2200 .  His cousin, Ian Goldfoot, was labeled as Q-M378.   It's Turkey's ancient history that I'm interested in, as our Jewish line has worked its way to the area of Israel in the days of Moses (1391-1271 BCE)  and kings David (1010-970 BCE)  and his son, Solomon(961-920 BCE). 

Update:5/21/22: Asia::  Q-M242 originated in Asia (Altai regions), and is widely distributed across it. Q-M242 is found in Russia, Siberia (Kets, Selkups, Siberian Yupik people, Nivkhs, Chukchi people, Yukaghirs, Tuvans, Altai people, Koryaks, etc.), Mongolia, China, Uyghurs, Tibet, Korea, Japan, Indonesia, Vietnam, Thailand, India, Pakistan,Afghanistan, Iran, Iraq, Saudi Arabia, Turkmenistan, Uzbekistan, and so on. 

from FTDNA's Q group:  

Q-Y2232

This branch is primarily found in the modern Ashkenazi Jewish population. For those with Ashkenazi Jewish oral traditions, our definitive SNP appears to Q-Y2232. Other Jewish Diaspora Q branches seem to come from elsewhere on the Q tree. They likely came into the Jewish population separately from Q-Y2232. Immediately above Q-Y2232 is Q-Y2200. It is unclear right now how and when those who are Q-Y2200 but not Q-Y2232 are related to their Ashkenazi Jewish cousins. 

                                             

(Since we were first labeled as Q-Y2200, we certainly are Jewish !)  You can stop doubting.  Q-Y2200 was born about 2,500 years ago either in southern Europe or Middle East.  Most men from this line today are Ashkenazi Jews.  This is the population of central and eastern European Jews.  It is the offshoot of Q-Y2211.   

"The Bible connects the Hittites with the Canaanites (Gen.10:15) and indicates that some dwelt in Canaan at an early period. Abraham purchased the cave at Machpelah from a Hittite, and Esau took wives from among them.  The Hittites were one of the 7 peoples from whom the Israelites conquered Canaan.  Later, David had Hittite warriors, and Solomon, Hittite wives.  "

But Uriah, being a disciplined soldier, refused to visit his wife. So David murdered him by proxy by ordering all of Uriah's comrades to abandon him in the midst of battle, so that he ended up getting killed by an opposing army. Following Uriah's death, David took Bathsheba as his eighth wife.  Uriah was a Hittite.  Was Bathsheba?  

Others matching  are:Q-L245, Q-BZ31, Q-BZ216, QBZ930, Q-M378, Q-YP1008, Q-YP1231,  Q-Y1010, QBZ38, Q-BZ43

 Q-M242 is mainly the predominant Y-DNA haplogroup among Native Americans and several peoples of Central Asia and Northern Siberia.

We haplogroup Q of the Jewish people could come from Anatolia along with many other peoples.  

Even in the Paleolithic period, Anatolia (or Asia Minor as it was once called) served as a bridge for migrations between Africa, Asia, and Europe. Long before the establishment of nation states, intermixing between human populations occurred in Anatolia. Indeed, Anatolia has been home to many civilizations including Hattians, Hurrians, Assyrians, Hittites, Greeks, Thracians, Phrygians, Urartians, Armenians, and Turks. Since Assyria had attacked Israel in 721 BCE and carried away the best of the population, and then the Babylonians, who had taken over the Assyrian holdings, had carried away Judeans in 597 and 586 BCE, probably mixing genes at both times, I'm not surprised to find we bear this Y haplogroup.  Hittites were from Anatolia and were in Canaan, mixed with the Canaanites as one of the city-states.  They fought the Israelites, then were absorbed into the nation, with David and Solomon marrying Hittite women.  Our history has made sure that we could be in contact with the QBZ67 Y haplogroup of Anatolia (Asia Minor).  

 Central Asian haplogroups (C, Q, and O) are rarer.  Q: 1.9% 

•  Could this be that the Hittites had left Anatolia and had migrated to Canaan, leaving only a few of them?

Gene flow between Anatolian, Caucasus, and northern Levantine populations occurred during the Late Neolithic and Chalcolithic to the Early Bronze age, including long-distance migration from Central Asia to Anatolia (1). The Turkic peoples, a collection of ethnolinguistically related populations originating from Central Asia, were first documented in western Eurasia in the fourth/fifth century BCE and currently live in Central, Eastern, Northern, and Western Asia as well as in parts of Europe and in North Africa

Haplogroup Q is found predominantly in Central Siberia, Central Asia and among Native Americans. Approximately 90% of pre-Columbian Native Americans belonged to haplogroup Q, and all descend from the branch Q1a2a1 (L54), including various subclades of Q1a2a1a1 (M3) and Q1a2a1a2 (Z780).

"Haplogroup Q-M242 is one of the two branches of P1-M45 also known as K2b2a (The other is R-M207).

Q-M242 is believed to have arisen around the Altai Mountains area (or South Central Siberia), approximately 17,000 to 31,700 years ago. However, the matter remains unclear due to limited sample sizes and changing definitions of Haplogroup Q: early definitions used a combination of the SNPs M242, P36.2, and MEH2 as defining mutations". Then it had plenty of time to make its way to Israel along the Mediterranean Sea.  

 In Europe haplogroup Q is found chiefly in southern Sweden (5%), among Ashkenazi Jews (5%).   It is found in various isolated pockets in central and Eastern Europe such as the Rhône-Alpes region of France, southern Sicily, southern Croatia, northern Serbia, parts of Poland and Ukraine, which should be the Jewish group, Šarić et al. (2013) also found 6.1% of haplogroup Q out of 412 samples from the island of Hvar in southern Croatia (accompanied by 2% of East Asian mtDNA haplogroup F).

Q-L275 is the branch originated by the first bifurcation (before 26 kya; between 27.8 and 32.5 kya according to Poznik et al. [29]) of haplogroup Q. It comprises Q-Y1150 and Q-M378. The first is mainly observed in Southwest Asia with some appearances in Northwest Eurasia, while the second, recently dissected [30], is spread across West, Central and parts of South Asia and harbours mainly Middle Eastern Y chromosomes, with one branch typical of Ashkenazi Jews, as well as European samples (Additional file 9: Figure S3a,b).

 Based on this distribution, the two M378 Y chromosomes observed in the Isthmo-Colombian area (Additional file 9: Figure S3b) should be interpreted as the result of a post-Columbian arrival from Eurasia, as previously hypothesized [20].

Analysis of 89 biallelic polymorphisms in 523 Turkish Y chromosomes revealed 52 distinct haplotypes with considerable haplogroup substructure, ..... The major components (haplogroups E3b, G, J, I, L, N, K2, and R1; 94.1%) are shared with European and neighboring Near Eastern populations and contrast with only a minor share of haplogroups related to Central Asian (C, Q and O; 3.4%), Indian (H, R2; 1.5%) and African (A, E3*, E3a; 1%) affinity. This comprehensive characterization of Y-chromosome heritage addresses many multifaceted aspects of Anatolian prehistory, including: (1) the most frequent haplogroup, J, splits into two sub-clades, one of which (J2) shows decreasing variances with increasing latitude, compatible with a northward expansion; 

As it stands today, this is what most people think, from Quora:  "The only honest and correct answer is: nobody knows. Only a handful of Anatolian DNA samples from the Middle & Late Bronze Age have been sequenced and analyzed, and they’re so few and so generically “Anatolian” that we can’t be sure they are representative of the Hittites (and not just native Anatolians probably under Hittite rule).

The Hittites were originally an invading population that conquered a very numerous non-Hittite and, in fact, non-Indo-European population. So, even if they absorbed many of the conquered people to their ethnocultural identity, we should consider that it is likely that the first Hittites were genetically very different from the late Hittites who lived well after they had become the elite of a very large and multiethnic state.

So, it might be useful to ask what haplogroups the remote ancestors of the Hittites had in 4000 B.C., what haplogroups the early Hittites had in 2000 B.C., what haplogroups the Hittites had during the Bronze Age collapse. Changes certainly happened. Notice this is a plural noun, because it’s very implausible that the Hittites only had one Y-DNA haplogroup, especially in their apogee as the masters of a large empire. Even tribal and clannish ethnicities of the past usually had several Y-DNA lineages in their midst, though one of them might prevail significantly over the others, mostly on a regional basis, given strong patterns of patrilocality in those societies."

I remember hearing that the Mormons connected the Native Americans to us Jews. They do have something in their Book of Mormon about 2 peoples coming from the same area of Israel.   "Since the late 1990s pioneering work of Luigi Luca Cavalli-Sforza and others, scientists have developed techniques that attempt to use genetic markers to indicate the ethnic background and history of individual people. The data developed by these mainstream scientists tell us that the Native Americans have very distinctive DNA markers, and that some of them are most similar, among old world populations, to the DNA of people anciently associated with the Altay Mountains area of central Asia. These evidences from a genetic perspective agree with a large body of archaeological, anthropological, and linguistic conclusions that Native American peoples' ancestors migrated from Asia at the latest 16,500–13,000 years ago. (See Settlement of the Americas and Genetic history of indigenous peoples of the Americas)."

Update: 5/20/22

Resource;

The New Standard Jewish Encyclopedia

https://www.familytreedna.com/groups/jewish-q/about/results

https://www.eupedia.com/europe/Haplogroup_Q_Y-DNA.shtml

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433500/

https://en.wikipedia.org/wiki/Haplogroup_Q-M242

https://pubmed.ncbi.nlm.nih.gov/14586639/

https://en.wikipedia.org/wiki/Genetic_studies_on_Turkish_people

https://www.quora.com/What-was-the-haplogroup-of-the-Hittites

https://en.wikipedia.org/wiki/Genetics_and_the_Book_of_Mormon

https://en.wikipedia.org/wiki/Haplogroup_Q-M242

https://haplogroup.org/ystory/q-y2200/